www.project
The current study was conducted to determine whether the use of acetaminophen after MMR vaccination may be associated with autism. This controlled study used the results of an Internet questionnaire conducted among parents of 16 July 2005 to January 30, 2006, consist of 83 children with autism against 80 controls. Acetaminophen use after MMR was significantly associated with autism in children 5 years old (OR 6.11, 95% CI 1.42-26.3), after limiting cases of children who regressed (OR 3.97, 95% CI 1.11-14.3) and considering only children who had post-vaccination sequelae (OR 8.23, 95% CI 1.56-43.3), adjusting for age, sex, ethnicity of the mother and the presence of concurrent disease with the MMR vaccine. Ibuprofen use after the MMR vaccine was not associated with autism. This preliminary study shows that use of acetaminophen after vaccination MMR was associated with autism.
Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: The results of a parent survey.
Schultz ST, Klonoff- Cohen HS, Wingard DL , Akshoomoff NA, Macera CA , Ming Ji .
University of California San Diego, and San Diego State University, USA. Stephen.schultz@med.navy.mil.
The present study was performed to determine whether acetaminophen (paracetamol) use after the measles-mumps-rubella vaccination could be associated with autistic disorder. This case-control study used the results of an online parental survey conducted from 16 July 2005 to 30 January 2006, consisting of 83 children with autistic disorder and 80 control children. Acetaminophen use after measles-mumps-rubella vaccination was significantly associated with autistic disorder when considering children 5 years of age or less (OR 6.11, 95% CI 1.42-26.3), after limiting cases to children with regression in development (OR 3.97, 95% CI 1.11-14.3), and when considering only children who had post-vaccination sequelae (OR 8.23, 95% CI 1.56-43.3), adjusting for age, gender, mother's ethnicity, and the presence of illness concurrent with measles-mumps-rubella vaccination. Ibuprofen use after measles-mumps-rubella vaccination was not associated with autistic disorder. This preliminary study found that acetaminophen use after measles-mumps-rubella vaccination was associated with autistic disorder.
PMID: 18445737 [PubMed - in process]
0 comments:
Post a Comment